Author(s):
RNA processing, a crucial mechanism in gene expression, intricately regulates the maturation of RNA molecules. Among these processes, tRNA splicing endonucleases hold a pivotal role in eukaryotic cells. This review article delves into recent advancements in understanding the intricacies of the eukaryotic tRNA splicing endonuclease machinery, highlighting the structural and functional aspects, evolutionary insights, and emerging therapeutic implications.
