Nigerian Society of Biochemistry and Molecular Biology

Biochemistry & Physiology: Open Access

Structural Insights into Enzyme-Substrate Interactions: Implications for Drug Design

Abstract

Author(s):

Understanding the molecular mechanisms of enzyme-substrate interactions is crucial for designing effective drugs targeting specific biological processes. This review article delves into recent advancements in structural biology that have elucidated the intricate details of enzyme-substrate binding. By examining various case studies across different enzyme classes, we highlight how structural insights have revolutionized drug design strategies. We discuss the implications of these findings for developing novel therapeutic agents that can modulate enzymatic activity with high specificity and efficacy.