Nigerian Society of Biochemistry and Molecular Biology

Biochemistry & Physiology: Open Access

Metabolic Pathways and Their Impact on Cancer Cell Proliferation

Abstract

Author(s):

Cancer is a complex disease characterized by uncontrolled cell growth and proliferation. Metabolic reprogramming, a hallmark of cancer cells, enables them to adapt to their demanding energetic and biosynthetic needs. This review explores the intricate metabolic pathways involved in cancer cell proliferation and their implications for therapeutic strategies. Key pathways discussed include glycolysis, the pentose phosphate pathway, amino acid metabolism, lipid metabolism, and mitochondrial function. Understanding these metabolic alterations provides insights into the vulnerabilities of cancer cells and highlights potential targets for therapeutic intervention.