Author(s):
Recent studies have suggested that xanthophylls may modulate pancreatic lipase activity and influence lipid digestion and absorption. While the exact mechanisms underlying this modulation are still being elucidated, several hypotheses have been proposed. One hypothesis suggests that xanthophylls may interact directly with pancreatic lipase, either by binding to its active site or by altering its conformation, thereby affecting its catalytic efficiency. Another hypothesis posits that xanthophylls may influence the physicochemical properties of lipid substrates, such as their emulsification and micellar solubilization, which in turn could impact pancreatic lipase activity . In summary, the interplay between xanthophylls and pancreatic lipase-mediated oil hydrolysis represents a fascinating area of research with potential implications for nutrition, health, and disease prevention. Continued efforts to unravel the complexities of this interaction may offer valuable insights into novel strategies for the management of lipid-related disorders and the promotion of overall health and well-being.
