Nigerian Society of Biochemistry and Molecular Biology

Biochemistry & Physiology: Open Access

Advances in CRISPR Technology: Applications in Genetic Disorders

Abstract

Author(s):

CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) technology has revolutionized genetic research and therapy over the past decade. This article reviews recent advancements in CRISPR technology and its applications in treating genetic disorders. We discuss the principles of CRISPR-Cas systems, various CRISPRbased tools, delivery methods, ethical considerations, and current challenges. Furthermore, we examine case studies and clinical trials that demonstrate the potential of CRISPR technology in curing genetic diseases. The future prospects and implications of CRISPR technology in personalized medicine are also explored.